Hemodynamic analysis of intracranial aneurysms using phase-contrast magnetic resonance imaging and computational fluid dynamics |
| |
| Authors: | Xuemei Zhao Rui Li Yu Chen Sheau Fung Sia Donghai Li Yu Zhang Aihua Liu |
| |
| Institution: | 1. Beijing Huaxin Hospital (First Affiliated Hospital of Tsinghua University), Beijing 100016, China;2. Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing 100084, China;3. Division of Neurosurgery, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia;4. Medical Center, Tsinghua University, Beijing 100084, China;5. Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China |
| |
| Abstract: | Additional hemodynamic parameters are highly desirable in the clinical management of intracranial aneurysm rupture as static medical images cannot demonstrate the blood flow within aneurysms. There are two ways of obtain-ing the hemodynamic information—by phase-contrast mag-netic resonance imaging (PCMRI) and computational fluid dynamics (CFD). In this paper, we compared PCMRI and CFD in the analysis of a stable patient's specific aneurysm. The results showed that PCMRI and CFD are in good agree-ment with each other. An additional CFD study of two stable and two ruptured aneurysms revealed that ruptured aneurysms have a higher statistical average blood velocity, wall shear stress, and oscillatory shear index (OSI) within the aneurysm sac compared to those of stable aneurysms. Furthermore, for ruptured aneurysms, the OSI divides the positive and negative wall shear stress divergence at the aneurysm sac. |
| |
| Keywords: | PCMRI CFD WSSD OSI Aneurysm rupture |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
