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| Synthesis and Crystal Structure of Ethyl 5-Amino-1-[（5′-methyl-1′- t-butyl-4′-pyrazolyl）carbonyl]-3-methylthio-1H-pyrazole-4-carboxylate | |
| 作者姓名： | LI Minga WEN Li-Ronga c ZHAO Gui-Longa WANG Xiaoa YANG Hua-Zhengb a (College of Chemistry and Molecular Engineering Qingdao University of Science and Technology Qingdao 266042 China) b(State Key Laboratory of Elemento-organic Chemistry Nankai University Tianjin 300071 China) c(State Key Laboratory of Applied Organic Chemistry Lanzhou University Lanzhou 730000 China) |
| 作者单位： | LI Minga，WEN Li-Ronga，c ZHAO Gui-Longa WANG Xiaoa YANG Hua-Zhengb a (College of Chemistry and Molecular Engineering，Qingdao University of Science and Technology，Qingdao 266042，China) b(State Key Laboratory of Elemento-organic Chemistry，Nankai University，Tianjin 300071，China) c(State Key Laboratory of Applied Organic Chemistry，Lanzhou University，Lanzhou 730000，China) |
| 基金项目： | The project was supported by the NNSFC (No. 20172031)，the NSF of Shandong Province (No. Y2003B01) and the State Key Laboratory of Applied Organic Chemistry of Lanzhou University |
| 摘 要： | 1INTRODUCTIONPolarizedketenedithioacetalshavebeenex-tensivelyusedasbuildingblocksinorganicsyn-thesis,especiallyinthesynthesisofheterocycliccompounds[1～6].Pyrazoleanditsderivativesrepre-sentoneofthemostactiveclassesofcompoundspossessingwidespectraofbiologicalactivities.Overthepastfewyears,considerableevidenceshavebeenaccumulatedtodemonstratetheefficacyofpyrazolederivatives,suchasantibacterial[7],fun-gicidal[8],herbicidal[9],insecticidal[10]andotherbiologicalactivities[11,12].Uptonow,alarg… |
| 关 键 词： | 合成 晶体结构 乙基5-氨基-1-[（5′-甲基-1′- t-丁基-4′-吡唑基）羰基]-3-甲硫基-1H-吡唑-4-羧酸酯 生物活性 |
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