Synthesis and In Vitro Antibacterial Activities of Novel 2‐Aryl‐3‐(phenylamino)‐2,3‐dihydroquinazolin‐4(1H)‐one Derivatives |
| |
| Authors: | Ali A. Mohammadi Hamed Rohi Ali Abolhasani Soorki |
| |
| Affiliation: | 1. Department of Chemistry, Sabzevar Branch, Islamic Azad University, , Sabzevar, Iran;2. Faculty of Science, Department of Chemistry, Ferdosy University, , Mashad, Iran;3. Shaheed Beheshti University, Academic Center for Education, Culture, and Research, Research Institute of Applied Sciences, , Tehran, Iran |
| |
| Abstract: | ![]()
An efficient synthesis of novel 2‐aryl‐3‐(phenylamino)‐2,3‐dihydroquinazolin‐4(1H)‐one derivatives using KAl(SO4)2.12H2O (Alum) as a catalyst from an aldehyde and 2‐amino‐N‐phenylbenzohydrazine in ethanol is described. All synthesized derivatives were screened for anti‐bacterial activity. Some compounds exhibited promising anti‐bacterial activity with reference to standard antibiotics. |
| |
| Keywords: | |
|
|
