1. Comparative Orthopaedic Research Laboratory, Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, 550 University Av. Charlottetown, Prince Edward Island, C1A4P3, Canada;2. Department of Chemistry, Memorial University, Memorial University St. John's, NL, A1B3X7, Canada;3. Department of Physics and Physical Oceanography, Memorial University, St. John's, NL, A1B3X7, Canada
Abstract:
The in vitro viability, osteogenic differentiation, and mineralization of four different equine mesenchymal stem cells (MSCs) from bone marrow, periosteum, muscle, and adipose tissue are compared, when they are cultured with different collagen‐based scaffolds or with fibrin glue. The results indicate that bone marrow cells are the best source of MSCs for osteogenic differentiation, and that an electrochemically aggregated collagen gives the highest cell viability and best osteogenic differentiation among the four kinds of scaffolds studied.
