Efficient One‐Pot Synthesis of Spiro[indoline‐3,1′‐pyrazolo[1,2‐b] phthalazine] Derivatives via Three‐Component Reaction |
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Authors: | Hui Chen Da‐Qing Shi |
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Affiliation: | Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, , Suzhou, 215123, People's Republic of China |
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Abstract: | ![]() An efficient one‐pot synthesis of spiro[indoline‐3,1′‐pyrazolo[1,2‐b]phthalazine] derivatives via three‐component reaction of phthalhydrazide, isatin, and malononitrile (cyanoacetic ester) is described. This new protocol has the advantages of high efficiency, mild reaction conditions, one‐pot procedure, and convenient operation. |
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