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Efficient One‐Pot Synthesis of Spiro[indoline‐3,1′‐pyrazolo[1,2‐b] phthalazine] Derivatives via Three‐Component Reaction
Authors:Hui Chen  Da‐Qing Shi
Affiliation:Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, , Suzhou, 215123, People's Republic of China
Abstract:
An efficient one‐pot synthesis of spiro[indoline‐3,1′‐pyrazolo[1,2‐b]phthalazine] derivatives via three‐component reaction of phthalhydrazide, isatin, and malononitrile (cyanoacetic ester) is described. This new protocol has the advantages of high efficiency, mild reaction conditions, one‐pot procedure, and convenient operation.
Keywords:
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