Green chemistry approach to the synthesis of 2‐aryl‐4‐ferrocenyl‐quinoline derivatives under microwave irradiation |
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| Authors: | Feiyue Wu Ge Zhang Bo Jiang Feng Shi Yuan Gao Shujiang Tu |
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| Institution: | 1. School of Chemistry & Chemical Engineering, Xuzhou Normal University, Xuzhou, Jiangsu, 221116, People's Republic of China;2. School of Chemistry and Chemical Engineering, Shenzhen University, Shenzhen, Guangdong, 215006, People's Republic of China |
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| Abstract: | A clean and expeditious route for the synthesis of 2‐aryl‐4‐ferrocenyl‐quinoline derivatives through microwave‐assisted multicomponent reaction of ferrocenecarboxaldehyde with ketone and dimedone in the presence of ammonium acetate using water as reaction media at 100°C is described. This procedure lends itself well to combinatorial methods, providing the target heteropolymetallic compounds in excellent yield. J. Heterocyclic Chem., (2011). |
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