New Dammarane‐Type Saponins from the Rhizomes of Panax japonicus |
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| Authors: | Min Zhou Min Xu Dong Wang Hong‐Tao Zhu Chong‐Ren Yang Ying‐Jun Zhang |
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| Affiliation: | 1. State Key Laboratory of Phytochemistry and Plant Resources of West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P.?R. China, (phone: +86‐871‐5223235;2. fax: +86‐871‐5150124);3. Graduate University of the Chinese Academy of Sciences, Beijing 100049, P.?R. China;4. Weihe Biotech Research and Development Center, Yuxi 653101, P.?R. China |
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| Abstract: | Phytochemical investigation of the rhizomes of Panax japonicus C. A. Meyer (Araliaceae) resulted in the isolation of two new dammarane‐type triterpenoid saponins, yesanchinoside R1 ( 1 ) and yesanchinoside R2 ( 2 ), together with one new natural product, 6′′′‐O‐acetylginsenoside Re ( 3 ). In addition, 25 known compounds, including 23 triterpenoid saponins, 4 – 26 , β‐sitosterol 3‐O‐β‐D ‐glucopyranoside ( 27 ), and ecdysterone ( 28 ), were also identified. The known saponins 12, 15 , and 18 – 22 were reported for the first time from the title plant. Their structures were elucidated on the basis of detailed spectroscopic analyses, including 1D‐ and 2D‐NMR techniques, as well as acidic hydrolysis. |
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| Keywords: | Panax japonicus Dammarane saponins Yesanchinosides R1 and R2 Triterpenoids Saponins |
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