Kinetic study of the interaction of three glycine‐containing dipeptides with diaquaethylenediamineplatinum(II) in aqueous medium |
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| Authors: | Subhasis Mallick Subala Mondal Arup Mandal Biplab K Bera Parnajyoti Karmakar Alak K Ghosh |
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| Institution: | Department of Chemistry, The University of Burdwan, Burdwan 713104, India |
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| Abstract: | The kinetics of the interaction of three glycine‐containing dipeptides, namely, glycine‐L‐leucine (Gly‐Leu), glycine‐L‐isoleucine (Gly‐Ile), and glycine‐valine (Gly‐Val) with Pt(en)(H2O)2](ClO4)2 has been studied spectrophotometrically as a function of substrate complex], dipeptides] and temperature at a particular pH(4.0), where the substrate complex exists predominantly as the diaqua species and the dipeptides as a zwitterion. The substitution reaction shows two consecutive steps; the first is the ligand‐assisted anation and the second is the chelation step. The activation parameters for both the steps were evaluated using Eyring's equation. The low ΔH1≠ and large negative value of ΔS1≠ as well as ΔH2≠ and ΔS2≠ indicate an associative mode of activation for both the aqua ligand substitution processes. © 2011 Wiley Periodicals, Inc. Int J Chem Kinet 43: 498–506, 2011 |
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