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A New Combination Strategy as Applied in Predicting Chromatographic Retention Times of Oligonucleotides at a Range of Temperatures from 30 °C to 80 °C
Authors:Gui‐Zhao Liang  Xiu‐Yan Ma  Yu‐Zhen Chen  Yuan‐Chao Li  Feng‐Li Lv  Li Yang
Institution:1. Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, Bioengineering College, Chongqing University, Chongqing 400044, P. R. China;2. Department of Mathematics, Henan Institute of Science and Technology, Xinxiang 453003, P. R. China;3. State Key Laboratory of Trauma, Burns and Combined Injury, Department 1, Institute of Surgery Research & Daping Hospital, The Third Military Medical University, Chongqing 400042, P. R China
Abstract:
Keywords:Oligonucleotides  Quantitative structure‐retention relationships  Score of generalized base properties  Auto cross covariance  Genetic algorithm  Support vector machine
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