Synthesis of 3,4-disubstituted 2,5-dihydrofurans starting from the Baylis-Hillman adducts via consecutive radical cyclization, halolactonization, and decarboxylation strategy |
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Authors: | Saravanan Gowrisankar |
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Affiliation: | Department of Chemistry and Institute of Basic Science, Chonnam National University, Gwangju 500-757, South Korea |
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Abstract: | A facile synthetic method of 3,4-disubstituted 2,5-dihydrofurans and 2,5-dihydropyrroles starting from the Baylis-Hillman adducts was developed. The 2,5-dihydrofuran skeleton was constructed via the consecutive radical cyclization, hydrolysis, halolactonization, and spontaneous decarboxylation strategy starting from the modified Baylis-Hillman adducts. |
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Keywords: | 2,5-Dihydrofurans Radical cyclization Halolactonization Baylis-Hillman adducts |
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