A stereoselective approach to the synthesis of pseudodistomin D |
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| Authors: | Mansour Haddad,Marc Larchevê que,Han Min Tong |
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| Affiliation: | Laboratoire de Synthèse Organique associé au CNRS ENSCP, 11 rue Pierre et Marie Curie, 75231 Paris Cedex 05, France |
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| Abstract: | ![]()
A stereoselective total synthesis of the core unit of pseudodistomin D, starting from l-serine, is described. The key step is a stereoselective intramolecular Michael reaction in which the piperidine ring is formed with the obtention of 1. |
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| Keywords: | l-Serine Amino alcohol Piperidine Intramolecular cyclization |
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