Reductions of the cisplatin-based platinum(IV) prodrug cis,cis,trans-[Pt(NH3)2Cl2Br2] by predominant biological thiols: kinetic and mechanistic studies |
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| Authors: | Wan Wenfang Sun Jingjing Liu Wanru Huo Shuying Shen Shigang |
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| Institution: | 1.College of Chemistry and Environmental Science, Key Laboratory of Analytical Science and Technology of Hebei Province, MOE Key Laboratory of Medicinal Chemistry and Molecular Diagnostics, Hebei University, Baoding, 071002, Hebei Province, People’s Republic of China
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| Abstract: | Transition Metal Chemistry - The reductions of the anticancer-active platinum(IV) complex cis,cis,trans-Pt(NH3)2Cl2Br2] by three predominant biological thiols (cysteine, homocysteine and... |
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