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Kendall’s tau-type rank statistics in genome data
Authors:Moonsu Kang  Pranab K Sen
Institution:(1) Department of Biostatistics, Statistics and Operations Research, University of North Carolina, Chapel Hill, NC 27599-7420, USA
Abstract:High-dimensional data models abound in genomics studies, where often inadequately small sample sizes create impasses for incorporation of standard statistical tools. Conventional assumptions of linearity of regression, homoscedasticity and (multi-) normality of errors may not be tenable in many such interdisciplinary setups. In this study, Kendall’s tau-type rank statistics are employed for statistical inference, avoiding most of parametric assumptions to a greater extent. The proposed procedures are compared with Kendall’s tau statistic based ones. Applications in microarray data models are stressed.
Keywords:dimensional asymptotics  genomics  multiple hypotheses testing  microarray data model  nonparametrics  U-statistics
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