Synthesis of new pyrido[2,3-d]pyrimidine derivatives by three-component condensation of 5-acetyl-4-aminopyrimidines, cyclohexane-1,3-diones, and orthocarboxylic acid esters |
| |
| Authors: | A. V. Komkov M. A. Prezent A. V. Ignatenko I. P. Yakovlev V. A. Dorokhov |
| |
| Affiliation: | (1) N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991 Moscow, Russian Federation |
| |
| Abstract: | A three-component condensation of 5-acetyl-4-aminopyrimidine derivatives with dimedone (or cyclohexane-1,3-dione) and triethyl orthoacetate (or triethyl orthopropionate) gave derivatives of 7-(1,3-dioxocyclohex-2-ylidene)-7,8-dihydropyrido[2,3-d]pyrimidine. These heterocyclic compounds containing the enamino ketone fragment can form boron chelates under the action of butoxy(diphenyl)borane. Dedicated to Academician O. M. Nefedov on the occasion of his 75th birthday. Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2006–2011, November, 2006. |
| |
| Keywords: | 2,6-disubstituted 5-acetyl-4-aminopyrimidines cyclohexane-1,3-diones triethyl orthoacetate triethyl orthopropionate three-component condensation 7-(1,3-dioxocyclohex-2-ylidene)-7,8-dihydropyrido[2,3-d]pyrimidines and their diphenylboron complexes |
| 本文献已被 SpringerLink 等数据库收录！ |
|
