A bifurcated pathway to thiazoles and imidazoles using a modular flow microreactor |
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| Authors: | Baxendale Ian R Ley Steven V Smith Christopher D Tamborini Lucia Voica Ana-Florina |
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| Affiliation: | Innovative Technology Centre (ACS), Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, U.K. |
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| Abstract: | ![]()
A scalable method for the preparation of 4,5-disubstituted thiazoles and imidazoles as distinct regioisomeric products using a modular flow microreactor has been devised. The process makes use of microfluidic reaction chips and packed immobilized-reagent columns to effect bifurcation of the reaction pathway. |
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