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| Total synthesis of snake toxin α-bungarotoxin and its analogues by hydrazide-based native chemical ligation | |
| 作者姓名： | Xiao-Qi Guo Jun Liang Ying Li Yong Zhang Dongliang Huang Changlin Tian |
| 作者单位： | a High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei 230031, China; b School of Life Science, University of Science and Technology of China, Hefei 230027, China; c Department of Chemistry, University of Science and Technology of China, Hefei 230026, China |
| 基金项目： | We thank Prof. Ji-Shen Zheng for his suggestions for this work. This work was supported by the Science and Technological Fund of Anhui Province for Outstanding Youth (No. 1808085J04) and the Innovative Program Development Foundation Hefei Center Physical Science Technology (No. 2017FXCX002). |
| 摘 要： | A new method for α-bungarotoxin was reported by combining Fmoc-SPPS and peptide hydrazide based ligat ion strategy. |
| 收稿时间： | 31 March 2018 |
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