Designed evolution of artificial metalloenzymes: protein catalysts made to order |
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Authors: | Creus Marc Ward Thomas R |
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Affiliation: | Department of Cellular and Molecular Biology, University of Neuchatel, Rue Emile-Argand 11, C.P. 158, Neuchatel, CH-2009, Switzerland. marc.creus@unine.ch |
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Abstract: | Artificial metalloenzymes based on biotin-streptavidin technology, a "fusion" of chemistry and biology, illustrate how asymmetric catalysts can be improved and evolved using chemogenetic approaches. |
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