Synthesis of heterocycles on the basis of products of addition of polyhaloalkanes to unsaturated systems.

Oximes of 3,3-dichloropropenal and 4,4,4-trifluoro-3-chloro-1-butenal were obtained on the basis of products of free-radical addition of CCl₄ and CF₃CCl₃ to vinyl butyl ether. Generation of the corresponding nitrile oxides from these oximes and reaction of the nitrile oxides in situ with vinyl butyl ether, phenylacetylene, and propargyl alcohol via the scheme of 1,3-dipolar cycloaddition are proposed as a method for the synthesis of isoxazoles containing ,-dichlorovinyl and -trifluoromethyl--chlorovinyl substituents in the 3 position.See 1] for Communication 1.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1250–1255, September, 1990.