| Effect of Supercritical Fluids on the Biological Activity of Absidia coerulea for the Hydroxylation of Reichsterin＇s Substance Acetate |
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| 作者姓名： | XiuFengLIU HuiMingZHU TuanWeiZHANG BaoQuanZHANG |
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| 作者单位： | SchoolofChemicalEngineeringandTechnology,TianjinUniversity,Tianjin300072 |
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| 摘 要： | The viability and biological activity of Absidia coerulea in compressed or supercritical CO2 and C2H4 were studied. The specific activity ofAbsidia coerulea in 7.5MPa CO2 and C2H4 at 306K can reach to 23% and 75% respectively, leading to the feasibility of using supercritical C2H4 as an alternative to the organic solvent in the hydroxylation of Reichsterin‘s substance acetate.
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| 关 键 词： | 超临界流体 生物活性 犁头霉属 羟基化作用 醋酸盐 氢化可的松 药物提取 |
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