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Heterocyclization of Derivatives of 4-Oxoalkanoic Acids to 1,5-Disubstituted Pyrrolin-2-ones |
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| Authors: | A. Yu. Egorova V. A. Sedavkina Z. Yu. Timofeeva |
| Affiliation: | (1) N. G. Chernyshevskii Saratov State University, Saratov, Russia |
| Abstract: | Conditions were developed for the synthesis and production of 1-aryl-5-alkyl(aryl)-3H- and 1-aryl-5-alkyl(aryl)-5H-pyrrolin-2-ones from the amides and esters of 4-oxoalkanoic acids. It was established that the yield and ratio of the 3H and 5H isomers depend on the substrate employed in the reaction. |
| Keywords: | 4-oxoalkanamides 1-aryl-5-alkyl(aryl)-3H-pyrrolin-2-ones 1-aryl-5-alkyl(aryl)-5H-pyrrolin-2-ones 4-oxoalkanoic esters |
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