Laser-induced photodissociation of carboxyhemoglobin: An optical method for eliminating the toxic effect of carbon monoxide |
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Authors: | M M Asimov R M Asimov and A N Rubinov |
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Institution: | 1.Stepanov Physics Institute,National Academy of Sciences of Belarus,Minsk,Belarus;2.Sensotronica Ltd.,Minsk,Belarus |
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Abstract: | We propose and examine an optical method for eliminating the toxic effect of carbon monoxide. The developed method is based
on laser-induced photodissociation of carboxyhemoglobin in blood vessels and capillaries. By numerical simulation of the interaction
of laser radiation with tissue, we calculate the spectra of the action of carboxyhemoglobin and oxyhemoglobin in cutaneous
blood vessels. We show that, despite the sufficiently strong overlap of the action spectra of carboxyhemoglobin and oxyhemoglobin,
the substantial difference in the quantum yield values makes it possible to develop an optical method for eliminating the
toxic effect of carbon monoxide. We determine the criteria for the efficiency of laser-induced photodissociation of carboxyhemoglobin
under direct action on lung alveoli through the skin tissue and intravenously. |
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