Prenylated xanthones from Garcinia xanthochymus |
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| Authors: | Chanmahasathien Wisinee Li Yushan Satake Masayuki Oshima Yasukatsu Ishibashi Masami Ruangrungsi Nijsiri Ohizumi Yasushi |
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| Institution: | Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan. |
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| Abstract: | A new prenylated xanthone, 1,3,5,6-tetrahydroxy-4,7,8-tri(3-methyl-2-butenyl)xanthone (1), was isolated from the wood of Garcinia xanthochymus together with a known xanthone, garciniaxanthone E (2). Their structures were determined by spectroscopic analysis. Compounds 1 (3 microM) and 2 (10 microM) elicited marked enhancement of nerve growth factor-mediated neurite outgrowth in PC12D cells. |
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