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Formal DNA hydrolysis by mono- and dinuclear iron complexes
Authors:Shell Thomas A  Glass Jessica E  Mackey Megan A  Layman Kathryn A  Mohler Debra L
Affiliation:Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, USA.
Abstract:
The complexes CpFe(CO)(2)Ph and [CpFe(CO)(2)](2) cleave DNA in the presence of H2O2 or organic peroxides to give products resulting from the formal hydrolysis of the phosphodiester groups.
Keywords:
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