Formal DNA hydrolysis by mono- and dinuclear iron complexes |
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Authors: | Shell Thomas A Glass Jessica E Mackey Megan A Layman Kathryn A Mohler Debra L |
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Affiliation: | Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, USA. |
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Abstract: | The complexes CpFe(CO)(2)Ph and [CpFe(CO)(2)](2) cleave DNA in the presence of H2O2 or organic peroxides to give products resulting from the formal hydrolysis of the phosphodiester groups. |
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