仿生生物膜上多巴胺的电子转移过程研究

利用薄层法(TLCV)研究了硝基苯(NB)/水(W)界面上二茂铁(Fc)-多巴胺(DA)体系的电子迁移(ET)过程,得到该体系界面电子转移速率常数为1.012cm.s^-1.mol^-1.L,界面电子转移反应为单电子过程(n=0.89).采用扫描电化学显微镜(SECM)对同一体系进行研究,得到电子迁移速率常数为(1.10±0.2)cm.s^-1.mol^-1.L,两种方法所得结果吻合,证明了薄层法的可行性.同时,低的反应物浓度比又一次验证了Barker理论.

Electron Transfer Process of Dopamine at Mimicking Biomembrane

An electron transfer reaction between ferrocene and dopamine (DA) in a aqueous solution and oxidizing agent in an organic solution immiscible with water was studied by thin-layer cyclic voltammetry(-{TLCV-}) for charge transfer on the liquid/liquid(L/L) interface. The bimolecular rate constants(k) were obtained and one electron transfer process on the interface could be observed. The oxidation reaction of DA on the L/L interface by above method was discussed in comparison with the result obtained by scanning electrochemical microscopy (SECM) and got a reasonable agreement between them, which could give a prove to the practicality of TLCV. Otherwise, lower concentration ratios K_r of aqueous to organic reactants were adopted, which gave an evidence to the proposed procedure of Barker.