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Synthesis and Antimicrobial Properties of the Novel Fluorinated Bis-ammonium Salts with Two Primary Amine Groups
引用本文:Jian Bin LUO Qiang WANG Hong TAN Jie Hua LI Yin Ping ZHONG. Synthesis and Antimicrobial Properties of the Novel Fluorinated Bis-ammonium Salts with Two Primary Amine Groups[J]. 中国化学快报, 2006, 17(11): 1423-1426
作者姓名:Jian Bin LUO Qiang WANG Hong TAN Jie Hua LI Yin Ping ZHONG
作者单位:[1]College of Polymer Science and Engineering, Sichuan University, Chengdu 610065 [2]College of Chemistry & Environment ProteCtion Engineering, Southwest University for Nationalities, Chengdu 610041 [3]Key Laboratory of Bio-resources and Eco-environment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu 610064
摘    要:
In order to resolve the increasing resistance phenomena of the Gram-negative bacteria against single chain quaternary ammonium salts (QAS), lysine with a pedant fluorinated bis-ammonium salts was synthesized and its antimicrobial properties were evaluated in this work. The novel fluorinated bis-ammonium salts shows similar activity with conventional single chain quaternary ammonium salts against Gram-positive bacteria but stronger activity against Gram-negative bacteria and yeast compared with the single chained counterpart.

关 键 词:抗菌剂 氟化二铵盐 胺基 合成方法
收稿时间:2006-05-15

Synthesis and Antimicrobial Properties of the Novel Fluorinated Bis-ammonium Salts with Two Primary Amine Groups
Jian Bin LUO,Qiang WANG,Hong TAN,Jie Hua LI,Yin Ping ZHONG. Synthesis and Antimicrobial Properties of the Novel Fluorinated Bis-ammonium Salts with Two Primary Amine Groups[J]. Chinese Chemical Letters, 2006, 17(11): 1423-1426
Authors:Jian Bin LUO  Qiang WANG  Hong TAN  Jie Hua LI  Yin Ping ZHONG
Abstract:
Keywords:Antimicrobial agents  fluorinated bis-ammonium salts  primary amine groups
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