Clean synthesis and antibacterial activities of spiro[pyrimido[4,5-b]quinoline-5,5'-pyrrolo[2,3-d]pyrimidine]-pentaones |
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| Authors: | Ghahremanzadeh Ramin Azimi Seyyedeh Cobra Gholami Nader Bazgir Ayoob |
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| Affiliation: | Department of Chemistry, Shahid Beheshti University, Tehran, Iran. |
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| Abstract: | ![]()
A simple, clean and efficient method for the synthesis of spiro[pyrimido[4,5-b]quinoline-5,5'-pyrrolo[2,3-d]pyrimidine]-pentaone derivatives by condensation reaction of 6-amino-uracils and isatins in aqueous media is reported. These products were evaluated in vitro for their antibacterial activities. |
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