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Study on Effect of Gd (III) Speciation on Ca (II) Speciation in Human Blood Plasma by Computer Simulation
Authors:Yue WANG  Xing LU  Shu Yun WANG  Jing Fen HAN  Kui Yue YANG  Chun Ji NIU  Jia Zuan NI Key Laboratory of Rare Earth Chemistry  Physics  Changchun Institute of Applied Chemistry  Chinese Academy of Sciences  Changchun
Affiliation:Yue WANG,Xing LU,Shu Yun WANG,Jing Fen HAN,Kui Yue YANG,Chun Ji NIU*,Jia Zuan NI Key Laboratory of Rare Earth Chemistry and Physics,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022
Abstract:Ca (II) speciation and effect of Gd (III) speciation on Ca (II) speciation in human blood plasma were studied by computer simulation. [CaHCO_3]~+ is a predominant compound species of Ca (II). Gd (III) can compete with Ca (II) for biological molecules. The presence of Gd (III) results in a increase of concentration of free Ca (II) and a decrease of concentration of Ca (II) compounds.
Keywords:Speciation   blood plasma   computer simulation   calcium (II)   gadolinium (III).
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