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Palladium-catalyzed C-H bond functionalization of C6-arylpurines |
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| Authors: | Guo Hai-Ming Rao Wei-Hao Niu Hong-Ying Jiang Li-Li Meng Ge Jin Jia-Jia Yang Xi-Ning Qu Gui-Rong |
| Affiliation: | College of Chemistry and Environmental Science, Key Laboratory of Green Chemical Media and Reactions of Ministry of Education, Henan Normal University, Xinxiang 453007, Henan, China. guohm518@hotmail.com |
| Abstract: | A highly regioselective Pd-catalyzed C(Ar)-H bond activation method was developed for the modification of purines (nucleosides) with different functional groups by using purine as a directing group. This approach provides a new access to a variety of functionalized purines (nucleosides) which are potentially of great importance in medicinal chemistry. |
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