Total Synthesis of the Putative Structure of Xylarinol B |
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| Authors: | Atul A More Dr Chepuri V Ramana |
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| Institution: | Division of Organic Chemistry, CSIR‐National Chemical Laboratory, Dr. Homi Bhabha Road, Pune ‐ 411 008 (India), Fax: (+91)?20‐25902629 |
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| Abstract: | The total synthesis of the putative structure of xylarinol B is described and the need to revise its structure is demonstrated. The central benzoxepine skeleton was constructed by employing a cobalt‐mediated bimolecular 2+2+2] Reppe–Vollhardt alkyne cycloaddition reaction. |
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| Keywords: | chiral pool cobalt natural products structure elucidation total synthesis |
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