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A tandem asymmetric synthesis approach for the efficient preparation of enantiomerically pure 9-(hydroxyethyl) anthracene |
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| Authors: | Jennifer C. BallPaul Brennan Tareg M. ElsunakiAlexis Jaunet Simon Jones |
| Affiliation: | a Department of Chemistry, Dainton Building, University of Sheffield, Brook Hill, Sheffield S3 7HF, UK b Pfizer Global Research and Development, Ramsgate Road, Sandwich CT13 9NJ, UK |
| Abstract: | A tandem approach for the preparation of gram quantities of enantiomerically pure 9-(hydroxyethyl)-anthracene is presented using an asymmetric reduction followed by kinetic resolution that has potential applicability to other chiral alcohols. |
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