Synthesis and characterization of novel dipeptide mimetics with hydantoin moiety |
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Authors: | Petar T Todorov Emilia D Naydenova |
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Institution: | Department of Organic Chemistry, University of Chemical Technology and Metallurgy, BG-1756 Sofia, Bulgaria |
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Abstract: | The synthesis of three novel 5,5-dimethylhydantoin derivatives 2-amino-N-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)acetamide, 2-amino-N-(4,4-dimethyl-2,5-dioxoimidazol idin-1-yl)-3-phenylpropanamide, and 2-amino-4-methyl-N-(4,4-dimethyl-2,5-dioxoimidazol idin-1-yl) pentanamide, is reported. The newly synthesized compounds have been characterized by infrared (IR), MS, and NMR (1H and 13C) spectra. |
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Keywords: | Hydantoins 5 5-Disubstituted hydantoins Peptide synthesis Amino acids |
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