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Total synthesis of (+)-pseudohygroline |
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| Authors: | JS Yadav G Narasimhulu N Mallikarjuna Reddy BV Subba Reddy |
| Institution: | Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India |
| Abstract: | A simple and efficient total synthesis of five-membered pyrrolidine, (+)-pseudohygroline is described. The key steps involved in this synthesis are highly stereoselective Prins cyclisation followed by reductive ring opening and hydroboration. |
| Keywords: | (+)-Pseudohygroline Prins cyclisation Hydroboration Pyrrolidine alkaloids |
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