An efficient InCl3-catalyzed hydration of nitriles to amides: acetaldoxime as an effective water surrogate |
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| Authors: | Eun Sun Kim |
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| Affiliation: | Department of Chemistry and Institute of Basic Science, Chonnam National University, Gwangju 500-757, Republic of Korea |
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| Abstract: | ![]()
An efficient InCl3-catalyzed hydration protocol of nitriles to amides was developed. The reaction was carried out in toluene at refluxing temperature with the aid of acetaldoxime as an effective water surrogate to produce amides in high yields. |
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| Keywords: | Indium chloride Hydration Nitriles Amides Acetaldoxime |
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