Total syntheses of the bromotyrosine-derived natural products ianthelline, 5-bromoverongamine and JBIR-44 |
| |
| Authors: | James W Shearman Thomas M Beale Steven V Ley |
| |
| Institution: | a Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
b Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK |
| |
| Abstract: | The total syntheses of the bromotyrosine-derived natural products ianthelline, 5-bromoverongamine and JBIR-44 are described and their cytotoxic activity in a cervical cancer (HeLa) cell line and human umbilical vein endothelial cells (HUVECs) are reported. |
| |
| Keywords: | Ianthelline 5-Bromoverongamine JBIR-44 Bromotyrosine Anticancer |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
