Metal-free one-pot oxidative conversion of benzylic alcohols and benzylic halides into aromatic amides with molecular iodine in aq ammonia, and hydrogen peroxide |
| |
Authors: | Ryosuke Ohmura |
| |
Institution: | Graduate School of Science, Chiba University, Yayoi-cho 1-33, Inage-ku, Chiba 263 8522, Japan |
| |
Abstract: | Various primary alcohols, particularly benzylic alcohols, could be converted into the corresponding aromatic amides in good yields in a one-pot manner by treatment with molecular iodine in aq. NH3, followed by reaction with ∼30% aq H2O2. Similarly, various benzylic halides could be also converted into the corresponding aromatic amides in good yields in a one-pot manner by treatment with molecular iodine in aq NH3, followed by reaction with ∼30% aq H2O2. The present reactions involve the metal-free one-pot oxidative conversion of benzylic alcohols and benzylic halides into the corresponding aromatic amides, respectively. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|