Volumetric diffuse optical tomography of brain activity |
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| Authors: | Culver Joseph P Siegel Andrew M Stott Jonathan J Boas David A |
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| Affiliation: | Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA. jculver@nmr.mgh.harvard.edu |
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| Abstract: | We present three-dimensional diffuse optical tomography of the hemodynamic response to somatosensory stimulation in a rat. These images show the feasibility of volumetrically imaging the functional response to brain activity with diffuse light. A combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance. |
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