A Molecular Magnet Confined in the Nanocage of a Globular Protein |
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| Authors: | Rajib K. Mitra Dr. Pramod K. Verma Dirk Wulferding Dirk Menzel Dr. Tamoghna Mitra Dr. Ana M. Todea Dr. Peter Lemmens Prof. Dr. Achim Müller Prof. Dr. Samir K. Pal Dr. |
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| Affiliation: | 1. Unit for Nano Science and Technology, Department for Chemical, Biological and Macromolecular Sciences, S.N. Bose National Centre for Basic Sciences, Block JD, Sector III, Salt Lake, Kolkata 700098 (India);2. Institute for Condensed Matter Physics, TU Braunschweig, Mendelssohnstr. 3, 38106 Braunschweig (Germany);3. Fakult?t für Chemie, Universit?t Bielefeld, Postfach 100131, 33501 Bielefeld (Germany) |
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| Abstract: | The effect of confinement and energy transfer on the dynamics of a molecular magnet, known as a model system to study quantum coherence, is investigated. For this purpose the well‐known polyoxovanadate [V15As6O42(H2O)]6? (V15) is incorporated into a protein (human serum albumin, HSA) cavity. Due to a huge overlap of the optical absorption spectrum of V15 with the emission spectrum of a fluorescence center of HSA (containing a single tryptophan residue), energy transfer is induced and probed by steady‐state and time‐resolved fluorescence. The geometrical coordination and the distance of the confined V15 to the tryptophan moiety of HSA are investigated at various temperatures. This effect is used as a local probe for the thermal denaturation of the protein at elevated temperatures. |
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| Keywords: | energy transfer molecular dynamics magnetic properties protein structures vanadates |
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