Tanacetamide D: A New Ceramide from Tanacetum artemisioides |
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| Authors: | Javid Hussain Meamoona Munir Zahid Hassan Naseem Bano Saima Arshad Viqar?Uddin Ahmad |
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| Institution: | 1. Department of Chemistry, Kohat University of Science and Technology, Kohat, Pakistan, (phone: +92‐922‐554565;2. fax: +92‐922‐554556);3. H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi‐75270, Pakistan |
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| Abstract: | One new ceramide (=long‐chain base linked to a fatty acid via an amide bond), tanacetamide D ( 1 ), was isolated from Tanacetum artemisioides. Besides this, the two known constituents 5‐demethylnobiletin ( 2 ) and 5‐hydroxy‐3,6,7,8,3′,4′‐hexamethoxyflavone ( 3 ) were isolated for the first time from this species. The structure elucidation of the isolated compounds were based primarily on 2D‐NMR techniques including correlation spectroscopy (COSY), heteronuclear multiple‐quantum coherence (HMQC), heteronuclear multiple‐bond correlation (HMBC), and nuclear Overhauser effect spectroscopy (NOESY) experiments. |
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| Keywords: | Tanacetum artemisioides Ceramides Tanacetamide D |
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