Type III factors with unique Cartan decomposition

We prove that for any free ergodic nonsingular nonamenable action Γ?(X,μ)$\Gamma ?(X,\mu )$ of all Γ   in a large class of groups including all hyperbolic groups, the associated group measure space von Neumann algebra L^∞(X)?Γ${\mathrm{L}}^{\infty }(X)?\Gamma$ has L^∞(X)${\mathrm{L}}^{\infty }(X)$ as its unique Cartan subalgebra, up to unitary conjugacy. This generalizes the probability measure preserving case that was established in Popa and Vaes (in press) 38]. We also prove primeness and indecomposability results for such crossed products, for the corresponding orbit equivalence relations and for arbitrary amalgamated free products _M1?BM2$M_1{?}_B{M}_2$ over a subalgebra B of type I.