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Synthesis of Δ1[9]- and/or Δ8[9]-dehydroindolizidines and related compounds
Authors:Seiji Miyano  Shinichiro Fujii  Osamu Yamashita  Naoko Toraishi  Kunihiro Sumoto
Abstract:
A facile synthesis of Δ1[9]- and/or Δ8[9]-dehydroindolizidine and related compounds, consisting of dry distillation of γ-(N-2-piperidinonyl)butyric acid over soda-lime, is described. Reductions of these dehydroindolizidines and stereochemistry of 1-methylindolizidine are also described.
Keywords:
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