| Distereoselective one-pot synthesis of pyrimidopyrimidines using sulfated tin oxide as a reusable catalyst： An extension of Biginelli-type reaction |
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| 基金项目： | Acknowledgments The authors are thankful to the Principal Dr. P. L. More, DSM, College, Parbhani and Principal Dr. S. N. Thore, Deogiri College, Aurangabad, for encouragement during the process of carrying out this work. |
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| 摘 要： | The Biginelli-type compounds 4,5,8a-triarylhexahydropyrimido4,5-d]pyrimidine-2,7（1H,3H）-diones were synthesized by a one-pot three-component reaction using sulfated tin oxide as a reusable catalyst. This method has the advantages of high yields, short reaction time, simple starting materials and reusability of catalyst for several times.
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| 关 键 词： | 可重复使用 反应时间 并嘧啶 催化剂 氧化锡 硫酸化 合成 锅 |
| 收稿时间： | 23 April 2013 |
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