a Istituto di Chimica Organica dell'Università and Centro di Studio sulle Sostanze Organiche Naturali del CNR, Via Venezian 21, 20133- Milano, Italy.
b Centro Studi Maria Branca, Via E. Porro 1, 20158- Milano Italy.
Abstract:
Bilin-1,19(21H,24H)-diones interact with O2·- in DMSO giving rise to adducts showing charge-transfer character. This reaction can be reversed by addition of O2·- consuming compounds. The O2·-biliverdin dimethyl ester adduct collapses partially to 10-oxobilirubin dimethyl ester when treated with thiourea and 2-mercaptoethanol.