Complexes of quinolone drugs norfloxacin and ciprofloxacin with alkaline earth metal perchlorates |
| |
| Authors: | S. K. Upadhyay P. Kumar V. Arora |
| |
| Affiliation: | (1) Department of Chemistry, Aligarh Muslim University, Aligarh, 202002, India;(2) Department of Chemistry, Kashi Naresh Government Postgraduate College, Gyanpur, Bhadohi, 221304, India |
| |
| Abstract: | The interaction of quinolone drugs Norfloxacin (NR) and Ciprofloxacin (CP) with magnesium, calcium and barium perchlorates was investigated. Solid complexes, obtained as products of this interaction, were isolated and characterized by elemental and thermal analysis, FT-IR spectral and electrical conductivity measurements. The spectral studies of the isolated complexes suggest that NR and CP act as bidentate ligands that bind through one carboxylic oxygen atom and the exocyclic carbonyl oxygen atom. The obtained results indicate the formation of the complexes of the following formulas: [M(CP)2](ClO4)2·xH2O and [M(NR)2](ClO4)2·xH2O, where M = Mg(II), Ca(II), and Ba(II). |
| |
| Keywords: | metal complexes magnesium(II) calcium(II) barium(II) FT-IR spectroscopy |
| 本文献已被 SpringerLink 等数据库收录！ |
|
