雷公藤的药效及毒性与微量元素的研究

雷公藤是一种药效大、毒性也大的中药。研究了雷公藤的28种无机元素，发现其有益元素铁、锰、锌、硒含量较高．其有害元素铅、砷、镉含量也较高，与其药效和毒性一一相对应。雷公藤对风湿性关节炎、肾病、肝脏病、皮肤病的疗效．与铁、锰、锌、硒在人体中生物学机理一致。雷公藤对消比道、心血管、肝脏、泌尿系统、造血系统的毒害作用，与铅、砷、镉在人体中的生物学效应一致。所以在使用雷公藤时，应考虑到微量元素作用．可提高雷公藤的疗效，降低其毒性。

Study on the Medical Effect and Toxicity of Leigongteng and Trace Elements

Leigongteng is a kind of traditional Chinese medicine with great medical effect and toxicity. Twenty-eight inorganic elements were studied and the content of Fe, Mn, Zn, Se wasfound high. Some harmful elements such as Pb, As, Cd have a higher level. The curative effects of Leigongteng on rheumarthritis. kidney disease, liver disease and skin disease are consistent with biological mechanism of Fe, Mn,Zn, Se in human body, while toxicity ofLeigongteng to digestive tract. cardiovascular system, liver, urinary system and hewopoieticsystem is consistent with biological effects of Pb, As, Cd in human body. So when usingLeigongteng, we should increase its medical effect, but reduce its toxicity.