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Activation of Aromatic C−F Bonds by a N-Heterocyclic Olefin (NHO) |
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| Authors: | Dr Debdeep Mandal Shubhadeep Chandra Dr Nicolás I Neuman Alok Mahata Arighna Sarkar Dr Abhinanda Kundu Dr Srinivas Anga Hemant Rawat Prof Dr Carola Schulzke Dr Kaustubh R Mote Prof Dr Biprajit Sarkar Prof Vadapalli Chandrasekhar Dr Anukul Jana |
| Institution: | 1. Tata Institute of Fundamental Research Hyderabad, Gopanpally, Hyderabad, 500107 India;2. Institut für Chemie und Biochemie, Anorganische Chemie, Freie Universität Berlin, Fabeckstrasse 34–36, 14195 Berlin, Germany
Institut für Anorganische Chemie, Lehrstuhl für Anorganische Koordinationschemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany;3. Institut für Chemie und Biochemie, Anorganische Chemie, Freie Universität Berlin, Fabeckstrasse 34–36, 14195 Berlin, Germany Instituto de Desarrollo Tecnológico para la Industria Química, CCT Santa Fe CONICET-UNL, Colectora Ruta Nacional 168, Km 472, Paraje El Pozo, 3000 Santa Fe, Argentina;4. Institut für Biochemie, Universität Greifswald, Felix-Hausdorff-Strasse 4, 17487 Greifswald, Germany;5. Institut für Chemie und Biochemie, Anorganische Chemie, Freie Universität Berlin, Fabeckstrasse 34–36, 14195 Berlin, Germany |
| Abstract: | A N-heterocyclic olefin (NHO), a terminal alkene selectively activates aromatic C−F bonds without the need of any additional catalyst. As a result, a straightforward methodology was developed for the formation of different fluoroaryl-substituted alkenes in which the central carbon–carbon double bond is in a twisted geometry. |
| Keywords: | alkenes C-F activation fluorine N-heterocyclic olefins nucleophilic substitution |