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THE EFFECTS OF SUPPRESSIVE ACTIVITIES MEDIATED BY CELLS ON THE PROTECTION OF FETUS AGAINST MATERNAL IMMUNE REJECTION
作者姓名:王德农  苏宝田  史敏言
作者单位:Department of Pathophysiology,Anhui Medical College,Hefei,Department of Pathophysiology,Anhui Medical College,Hefei,Department of Pathophysiology,Anhui Medical College,Hefei
摘    要:
Using both mixed lymphocyte reaction (MLR) and graft-versus-host reaction (GVHR) assays, investigations have been made on 60 multiparous mice of late pregnancy, derived from C57BL mating with SWI as well as C57BL mating with BGI. The results demonatrate the presence of suppressor cells both in uterus-draining-lymphnodes (DLN) and in spleen of allogeneie pregnant mice. The suppressive immune regulatory activity mediated by these cells might play an important role in the successful maintenance of fetus allograft. The possible mechanisms about the inducing of the changes in lymphocyte subpopulation are also studied in this paper.

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