| 哒嗪并[3,2-c]1,2,4-三唑类化合物的合成 |
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| 引用本文： | 曹玲华,WANG Cai-Fang,王彩芳,陶晶.哒嗪并[3,2-c]1,2,4-三唑类化合物的合成[J].有机化学,2006,26(12):1686-1691. |
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| 作者姓名： | 曹玲华 WANG Cai-Fang 王彩芳 陶晶 |
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| 作者单位： | 1. 新疆大学化学化工学院,乌鲁木齐,830046;南开大学元素有机化学国家重点实验室,天津,300071
2. 新疆大学化学化工学院,乌鲁木齐,830046 |
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| 基金项目： | 国家自然科学基金(Nos.29962002,20462006)资助项目. |
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| 摘 要： | 以取代苯和丁二酸酐为起始原料, 经Friedel-Crafts反应, 肼合环, Br2/HOAc氧化脱氢后得到一系列1,6-二氢-3-芳基-6-哒嗪酮(2a～2d). 然后将2a～2d与PCl5在POCl3中回流, 得到相应的氯代产物3a～3d, 将其与酰肼作用, 合环后得到一系列未见报道的哒嗪并3,2-c]1,2,4-三唑类化合物. 所有化合物结构均经元素分析, IR, 1H NMR 和MS谱得以证实, 并对其波谱性质进行了讨论.
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| 关 键 词： | 哒嗪酮 哒嗪 1 2 4-三唑 |
| 收稿时间： | 01 5 2006 12:00AM |
| 修稿时间： | 06 23 2006 12:00AM |
Synthesis of Pyridazino[3,2-c]1,2,4-triazoles |
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| WANG Cai-Fang.Synthesis of Pyridazino[3,2-c]1,2,4-triazoles[J].Chinese Journal of Organic Chemistry,2006,26(12):1686-1691. |
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| Authors: | WANG Cai-Fang |
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| Institution: | a. College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046;b. State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071 |
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| Abstract: | A series of pyridazino3,2-c]1,2,4-triazoles were synthesized from hydrazides and 3-aryl-6- chloropyridazines (3a～3d), which were obtained from substituted benzene and succinic anhydride by Friedel-Crafts reaction, cyclization with hydrazine hydrate, dehydrogenation and chloro-substitution. Their structures were established by elemental analysis, IR, 1H NMR and MS spectra. |
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| Keywords: | pyridazinone pyridazine 1 2 4-triazole |
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