A novel sesterterpenoid, nitiol, as a potent enhancer of IL-2 gene expression in a human T cell line, from the Peruvian folk medicine "Hercumpuri" (Gentianella nitida). |
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Authors: | N Kawahara M Nozawa A Kurata T Hakamatsuka S Sekita M Satake |
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Institution: | National Institute of Health Sciences (NIHS), Tokyo, Japan. |
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Abstract: | A novel sesterterpenoid designated as nitiol (1), possessing enhancement activity of IL-2 gene expression in a human T cell line, was isolated from the Peruvian folk medicine "Hercampuri" (Gentianella nitida). The structure was elucidated by extensive spectroscopic investigation. |
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