|
|||||
|
|
N-Iodosuccinimide (NIS) as a mild and highly chemoselective catalyst for deprotection of tert-butyldimethylsilyl ethers |
|
| Authors: | Babak Karimi Asghar Zamani |
| Institution: | a Department of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), PO Box 45195-159, Gava Zang, Zanjan, Iran b Institute for Fundamental Research (IPM), Farmanieh, PO Box 19395-5531, Tehran, Iran |
| Abstract: | A variety of alcoholic TBDMS (t-butyldimethylsilyl) ethers are easily removed in excellent yields by treatment with a catalytic amount of N-iodosuccinimide (NIS, 5 mol %) in methanol. This method is able to deprotect TBDMS ethers of alcohols in the presence of TBDMS ethers of phenols. |
| Keywords: | Silyl ethers Deprotection N-Iodosuccinimide TBDMS ethers Protecting groups |
| 本文献已被 ScienceDirect 等数据库收录！ | |