Novel transformation of 5-cyanouracil derivatives |
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Authors: | Andrzej Gondela |
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Affiliation: | Department of Organic Chemistry, Biochemistry and Biotechnology, Silesian University of Technology, Krzywoustego 4, 44-100 Gliwice, Poland |
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Abstract: | 5-Cyano-1-(dihydroxypropyl)-3-methyluracils were synthesized in the reaction of 1-(4-nitrophenyl)-5-cyano-3-methyluracil with appropriate aminodiols. In the aprotic solvents, the reaction proceeds according to the ANRORC type mechanism. In protic solvents the products of Dimroth rearrangement were isolated. |
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Keywords: | 1-(Dihydroxypropyl)-5-cyanouracils Aminopropanediols Enantiomers |
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